What are the factors that increase the risk of vaginal cancer? Risk factors associated with vaginal cancer include:
~ Old age which typically peak in the decade of 6 and 7.
~ Use of ring pessaries.
~ HPV infection and other sexually transmitted infections.
~ History of genital warts (warts). Chronic vaginitis and late menopause.
~ Masturbation and obesity.
~ Radiation and exposure to diethylstilbestrol (DES) in utero.
~ Vaginal cancer risk factors with risk factors for cervical cancer, and equally associated with exposure to HPV infection.
The risk for cancer of the vagina is a history of cancer, such as cervical or vulvar cancer, indicating that the same causes. HPV is consistently found in the vaginal cancer and Vain.
Women infected with oncogenic HPV types (likely to cause cancer) are at increased risk of this malignancy. Although not clinically proven from an epidemiologic study, the risk factors of cervical and vaginal cancer is the same as the result of exposure to HPV infection.
The biggest risk factor for cancer of the vagina is a woman who previously suffered from carcinoma of the cervix and vulva. The study on 121 patients with Vain, Dodge and his colleagues found 22% of them do surgery for cervical intraephithelial neoplasia (CIN) and 22% other hysterectomy.
Other factors associated with trauma caused by chronic vaginal pessary. There is no link between the measures prior hysterectomy with vaginal cancer, the studies that have been done once the population controlled for age and cervical disease.
1971, Herbst and his colleagues describe the relationship exposure to diethylstilbestrol (DES) and clear cell adenocarcinoma intrauterine (CCA) vagina. DES, a synthetic nonsteroidal estrogen, is used for the prevention of spontaneous abortion in the 1940s and 1950s.
Based Registry for Research on Hormonal Carcinogenesis transplacental Arthur Herbst pioneered at the University of Chicago, the reviews were conducted in 1987 discovered 519 cases of CCA of the vagina or cervix.
It is estimated that the risk of developing CCA from birth through age 34 years among women exposed to DES, which is 1 per 1,000. CCA diagnosed middle-age is 19 years. Women whose mothers were exposed to DES before the 12th week of pregnancy is declared as high risk. Up to now, has not been proven if the girls whose mothers are exposed to DES quite risky for malignancy other than CCA.
The possibility of post-natal effects of synthetic estrogen, particularly oral contraceptives, uterus in patients exposed to DES has been evaluated. An analysis of 244 cases compared with 244 women age equivalent DES, Palmer and his colleagues are not able to find an increased risk of vaginal CCA in patients taking oral contraceptives. It is also impressive that ionizing radiation have also been linked as a causative factor of vaginal cancer.
source : deherba.com
This post is written by
Maha for Blog Information and News. It was posted on Tuesday, June 26, 2012 at 12:00 AM. The post is filed under
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